2022: Electricia coli
Cancer remains one of the most life-threatening diseases all over the world. Therefore, its early-stage detection is critical for timely intervention needed to save the patients life. Here we propose a system for more accurate and cost-effective detection of cancer by taking advantage of biomarker sensing together with external electron transfer through a microbial fuel cell. As the final output, we will detect an electrical signal in the presence of a cancer biomarker. Our project relies on the use of a toehold switch biosensor to detect the cancer biomarker PANTR1, a long non-coding RNA, and subsequently express a gene that leads to an electron flow outside the cell resulting in an electric signal. To detect this electric current, we built a microbial fuel cell device connected to an Arduino chip that allows real-time electron transfer measurements with an accuracy higher than fluorescent molecules or chromophores commonly used in such devices.
For more infos, visit our WIKI.
Rewards
Gold Medal
Best Wiki Award Nomination, Overgrad
The 2022 iGEM competition
In 2022, 356 team from 41 countries participated at the competition and more than 3500 people attended the Grand Jamboree that was held in Paris, at the Porte de Versailles Convention Center from 26th to 28th of October 2022. Full infos and results are available on the iGEM 2022 website.
